KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HDAC1
All Species:
36.06
Human Site:
S393
Identified Species:
52.89
UniProt:
Q13547
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13547
NP_004955.2
482
55103
S393
E
D
A
I
P
E
E
S
G
D
E
D
E
D
D
Chimpanzee
Pan troglodytes
XP_519834
482
55098
S393
E
D
A
I
P
E
E
S
G
D
E
D
K
E
D
Rhesus Macaque
Macaca mulatta
XP_001096929
485
54378
S402
E
D
A
I
P
E
E
S
G
D
E
D
E
E
D
Dog
Lupus familis
XP_544435
482
55144
S393
E
D
A
I
P
E
E
S
G
D
E
D
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O09106
482
55056
S393
E
D
A
I
P
E
E
S
G
D
E
D
E
E
D
Rat
Rattus norvegicus
Q4QQW4
482
55074
S393
E
D
A
I
P
E
E
S
G
D
E
D
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521848
455
51607
P374
L
R
M
L
P
H
A
P
G
V
Q
M
Q
A
I
Chicken
Gallus gallus
P56517
480
54920
S393
E
D
A
V
Q
E
D
S
G
D
E
E
E
E
D
Frog
Xenopus laevis
O42227
480
54874
S393
E
D
S
V
H
D
D
S
G
E
E
D
E
E
D
Zebra Danio
Brachydanio rerio
Q803C3
428
48962
N348
D
V
S
T
R
I
E
N
Q
N
S
R
Q
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q94517
521
58312
S391
E
D
A
I
N
D
E
S
D
D
E
D
K
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17695
461
52119
P381
L
E
Q
L
T
F
V
P
S
V
Q
M
R
P
I
Sea Urchin
Strong. purpuratus
P56518
576
64060
D393
D
A
I
P
D
D
S
D
A
E
D
E
A
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P56521
513
57528
E401
V
P
D
T
E
I
P
E
Q
D
E
D
Q
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22446
501
56004
S386
S
K
L
Q
H
A
P
S
V
P
F
Q
E
R
P
Baker's Yeast
Sacchar. cerevisiae
P32561
433
48886
S354
Y
G
P
D
Y
K
L
S
V
R
P
S
N
M
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
88.4
99.1
N.A.
99.3
99.1
N.A.
83.4
93.3
91
54.3
N.A.
71.9
N.A.
59.5
69.6
Protein Similarity:
100
100
90.7
99.5
N.A.
100
100
N.A.
89
96.4
96.8
71.3
N.A.
82.1
N.A.
77.5
77.4
P-Site Identity:
100
86.6
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
66.6
53.3
6.6
N.A.
66.6
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
93.3
93.3
40
N.A.
80
N.A.
20
46.6
Percent
Protein Identity:
N.A.
53.2
N.A.
56.6
54.5
N.A.
Protein Similarity:
N.A.
69.9
N.A.
71
70.1
N.A.
P-Site Identity:
N.A.
33.3
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
50
0
0
7
7
0
7
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
57
7
7
7
19
13
7
7
57
7
57
0
13
63
% D
% Glu:
57
7
0
0
7
44
50
7
0
13
63
13
50
50
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
7
% F
% Gly:
0
7
0
0
0
0
0
0
57
0
0
0
0
0
0
% G
% His:
0
0
0
0
13
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
44
0
13
0
0
0
0
0
0
0
0
13
% I
% Lys:
0
7
0
0
0
7
0
0
0
0
0
0
13
0
0
% K
% Leu:
13
0
7
13
0
0
7
0
0
0
0
0
0
0
7
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
13
0
7
0
% M
% Asn:
0
0
0
0
7
0
0
7
0
7
0
0
7
0
7
% N
% Pro:
0
7
7
7
44
0
13
13
0
7
7
0
0
7
7
% P
% Gln:
0
0
7
7
7
0
0
0
13
0
13
7
19
0
0
% Q
% Arg:
0
7
0
0
7
0
0
0
0
7
0
7
7
7
0
% R
% Ser:
7
0
13
0
0
0
7
69
7
0
7
7
0
0
0
% S
% Thr:
0
0
0
13
7
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
13
0
0
7
0
13
13
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _